F13A1

Across TCGA cell cohorts, F13A1 mutation is significantly associated with the drug of many other genes, with 79 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible F13A1-associated genes across cancer lineages are CCT245467, Pevonedistat, and Lapatinib. Each is linked with F13A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both F13A1-to-partner and partner-to-F13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCT245467 grouped by F13A1-low versus F13A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F13A1→partner) and Y-score (partner→F13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCT245467 →	+0.404	+3.000	.048	.021	3	1
LARGE_INTESTINE	Pevonedistat →	+0.719	+2.710	.016	.027	3	1
LARGE_INTESTINE	Lapatinib →	+0.583	+3.169	.024	.009	3	1
LARGE_INTESTINE	I-BET-762 →	+0.446	+2.807	.036	.027	3	1
LARGE_INTESTINE	ML323 →	+0.338	+2.807	.023	.037	3	1
LARGE_INTESTINE	Entospletinib →	+0.484	+2.061	.002	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

CCT245467 by F13A1 expression — LARGE_INTESTINE

Explore this box plot interactively →