F12

Across TCGA patient cohorts, F12 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,777 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible F12-associated proteins across cancer lineages are DDX21_S89, HK2, and MECP2. Each is linked with F12 in more than 4 cancer types. Because this analysis shows association rather than direction, both F12-to-partner and partner-to-F12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, F12 versus DDX21_S89 in LSCC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (F12→partner) and Y-score (partner→F12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDX21_S89 →	+0.671	+0.677	<.001	<.001	3	5
PDAC	HK2 →	+0.526	+0.519	.001	<.001	3	5
LSCC	MECP2 →	-0.398	-0.922	<.001	<.001	3	5
HNSC	METTL7A →	-0.624	-0.650	.002	.001	3	5
LSCC	MYC_S62 →	+0.632	+0.757	<.001	<.001	3	4
LUAD	NCBP3_S415 →	+0.525	+1.018	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,777 associations by consensus.

F12 vs DDX21_S89 — LSCC

Explore this scatter interactively →