F11R

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, F11R mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated F11R data layer compared with 19 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher F11R mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated F11R expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, GBM, and HNSC are the cancer types where F11R mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSQuartileII,III,IV1.0000.800.01513view →
GBMOSTertileAll0.3860.710.00112view →
HNSCDFSQuartileII,III,IV1.0000.859.0109view →
PDACDFSMedianIV0.2500.934.0243view →
LUADDFSQuartileII,III,IV0.8210.961.0342view →
LSCCDFSTertileII,III,IV0.4981.000.0401view →
Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

F11R–CCRCC (DFS)

Kaplan–Meier survival curve for F11R mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration