F11R

Across TCGA pan-cancer cohorts, F11R RNA differs between tumor and matched normal tissue in 16 of 18 cancer types tested, making tumor–normal expression one of F11R’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where F11R RNA is repressed in tumor relative to normal tissue. In most cancer types F11R is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, HNSC, and BLCA are the cancer types where F11R tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in F11R RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−1.931	<.001	11	view →
HNSC	Male	IV	+1.558	<.001	11	view →
BLCA	All	III,IV	+1.932	.002	8	view →
STAD	Male	All	+1.482	<.001	8	view →
BRCA	All	III,IV	+1.025	<.001	6	view →
LIHC	Male	All	+0.873	<.001	6	view →
KIRC	All	II,III,IV	−0.416	<.001	6	view →
CHOL	Male	All	+1.866	<.001	4	view →
UCEC	All	All	+1.445	<.001	4	view →
LUSC	Female	All	+0.836	<.001	4	view →
PAAD	All	All	+1.152	.035	2	view →
ESCA	All	All	+1.101	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 16 lineages.

F11R–KICH

Open the KICH breakdown →