F11R

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, F11R mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible F11R-associated genes across cancer lineages are Di-Ras3 and p62 Lck ligand. Each is linked with F11R in more than 1 cancer types. Because this analysis shows association rather than direction, both F11R-to-partner and partner-to-F11R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Di-Ras3 grouped by F11R-low versus F11R-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (F11R→partner) and Y-score (partner→F11R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDi-Ras3 →-0.158-2.321.033.03531
UCECp62 Lck ligand →+0.387+2.321.017.03511
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Di-Ras3 by F11R expression — UCEC

Box plot of Di-Ras3 in F11R-low vs F11R-high samples in UCEC.

Explore this box plot interactively →

Exploration