F11-AS1

Across TCGA pan-cancer cohorts, F11-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated F11-AS1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher F11-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated F11-AS1 expression acts as an unfavorable survival marker, although some lineages such as LIHC and UCS show a favorable association.

LIHC, LUSC, and LGG are the cancer types where F11-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Quartile	III,IV	0.843	0.430	<.001	55	view →
LUSC	DFS	Median	All	0.311	0.478	.001	52	view →
LGG	OS	Median	All	0.358	0.540	<.001	50	view →
UCS	DFS	Quartile	III,IV	0.543	0.085	.005	46	view →
ACC	OS	Quartile	III,IV	0.425	0.839	<.001	29	view →
MESO	DFS	Tertile	IV	0.124	0.392	.004	27	view →
THYM	DFS	Tertile	III,IV	0.550	1.000	.020	22	view →
SKCM	DFS	Median	III,IV	0.697	0.547	.007	22	view →
CHOL	DFS	Median	II,III,IV	0.106	0.566	.002	21	view →
HNSC	OS	Quartile	All	0.461	0.647	.007	20	view →
KIRC	OS	Quartile	All	0.731	0.550	.011	19	view →
KIRP	OS	Tertile	All	0.965	0.754	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

F11-AS1–LIHC (OS)

Open the LIHC breakdown →