F10

Across TCGA pan-cancer cohorts, F10 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated F10 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher F10 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated F10 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

CCRCC, LUAD, and GBM are the cancer types where F10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	1.000	0.821	.020	18	view →
LUAD	OS	Quartile	II,III,IV	0.224	0.762	.019	16	view →
GBM	OS	Tertile	All	0.621	0.224	.002	15	view →
UCEC	DFS	Tertile	III,IV	0.232	0.847	.030	6	view →
LSCC	DFS	Median	II,III,IV	0.846	0.988	.046	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

F10–CCRCC (DFS)

Open the CCRCC breakdown →