F10-AS1

Across TCGA pan-cancer cohorts, F10-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated F10-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher F10-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated F10-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and BLCA show a favorable association.

KIRC, COAD, and LUAD are the cancer types where F10-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	III,IV	0.291	0.555	<.001	82	view →
COAD	OS	Tertile	All	0.781	0.888	.001	45	view →
LUAD	DFS	Tertile	III,IV	0.250	0.511	.024	32	view →
LUSC	OS	Quartile	III,IV	0.444	0.713	.003	29	view →
KIRP	OS	Median	All	0.976	0.803	.009	26	view →
READ	DFS	Quartile	All	0.550	0.765	.002	26	view →
BLCA	OS	Tertile	All	0.765	0.527	.015	18	view →
SKCM	DFS	Tertile	III,IV	0.516	0.188	.003	17	view →
BRCA	OS	Quartile	II,III,IV	0.735	0.538	.012	10	view →
DLBC	DFS	Tertile	III,IV	0.137	0.761	.014	9	view →
OV	OS	Median	IV	0.277	0.460	.015	6	view →
THCA	OS	Quartile	III,IV	0.883	0.986	.006	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

F10-AS1–KIRC (DFS)

Open the KIRC breakdown →