EYA4

Across TCGA patient cohorts, EYA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,805 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EYA4-associated proteins across cancer lineages are PPFIBP1, CLPP, and PPM1F. Each is linked with EYA4 in more than 5 cancer types. Because this analysis shows association rather than direction, both EYA4-to-partner and partner-to-EYA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EYA4 versus PPFIBP1 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA4→partner) and Y-score (partner→EYA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPFIBP1 →	+0.410	+1.770	.001	<.001	3	6
CCRCC	CLPP →	-0.392	-0.658	<.001	<.001	3	5
UCEC	PPM1F →	+0.305	+0.867	.001	<.001	3	5
BRCA	RAI14 →	+0.445	+0.449	<.001	.001	3	5
CCRCC	MSRB3 →	+0.655	+0.841	<.001	<.001	3	5
BRCA	SORCS2 →	+0.596	+0.307	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,805 associations by consensus.

EYA4 vs PPFIBP1 — OV

Explore this scatter interactively →