EYA3

Across TCGA patient cohorts, EYA3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,726 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EYA3-associated genes across cancer lineages are HDAC1, AUNIP, and MAZ. Each is linked with EYA3 in more than 4 cancer types. Because this analysis shows association rather than direction, both EYA3-to-partner and partner-to-EYA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EYA3 versus HDAC1 in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA3→partner) and Y-score (partner→EYA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HDAC1 →	+0.564	+0.341	.002	.003	3	5
LSCC	AUNIP →	+0.822	+0.349	<.001	<.001	3	5
BRCA	MAZ →	+0.686	+0.318	.002	<.001	3	4
UCEC	CCNE1 →	+1.141	+0.279	<.001	<.001	3	4
BRCA	PSMB2 →	+0.392	+0.200	.003	.006	3	4
LSCC	CEP78 →	+0.588	+0.238	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,726 associations by consensus.

EYA3 vs HDAC1 — OV

Explore this scatter interactively →