EYA3

Across TCGA cell cohorts, EYA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,892 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EYA3-associated GO terms across cancer lineages are Nuclear export, Regulation of chromosome condensation, and Regulation of double-strand break repair. Each is linked with EYA3 in more than 15 cancer types. Because this analysis shows association rather than direction, both EYA3-to-partner and partner-to-EYA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by EYA3-low versus EYA3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA3→partner) and Y-score (partner→EYA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear export →	+0.083	+0.793	<.001	<.001	3	16
OESOPHAGUS	Regulation of chromosome condensation →	+0.249	+0.655	<.001	.003	3	16
BONE	Regulation of double-strand break repair →	+0.070	+0.742	.003	.001	3	16
SOFT_TISSUE	Establishment of mitotic spindle localization →	+0.132	+1.040	<.001	<.001	3	16
BONE	Positive regulation of DNA repair →	+0.067	+0.732	.001	.003	3	15
SOFT_TISSUE	Microtubule polymerization →	+0.110	+0.971	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,892 associations by consensus.

Nuclear export by EYA3 expression — BONE

Explore this box plot interactively →