EYA3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EYA3 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible EYA3-associated genes across cancer lineages are UGT2B10. Each is linked with EYA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both EYA3-to-partner and partner-to-EYA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B10 grouped by EYA3-low versus EYA3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA3→partner) and Y-score (partner→EYA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINUGT2B10 →+0.006+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

UGT2B10 by EYA3 expression — SKIN

Box plot of UGT2B10 in EYA3-low vs EYA3-high samples in SKIN.

Explore this box plot interactively →

Exploration