EYA2

Across TCGA patient cohorts, EYA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,078 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EYA2-associated proteins across cancer lineages are AUTS2_S956, EYA2_S257, and MEIS1. Each is linked with EYA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both EYA2-to-partner and partner-to-EYA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EYA2 versus AUTS2_S956 in LUAD, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EYA2→partner) and Y-score (partner→EYA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	AUTS2_S956 →	+0.801	+1.120	.001	.005	3	4
OV	EYA2_S257 →	+1.496	+2.403	<.001	<.001	3	4
GBM	MEIS1 →	+0.941	+1.445	<.001	<.001	3	4
UCEC	PDLIM1 →	+0.492	+1.240	.003	.002	3	4
LSCC	ST14 →	+0.597	+1.222	<.001	<.001	3	3
PDAC	TXNDC17 →	+0.363	+0.942	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,078 associations by consensus.

EYA2 vs AUTS2_S956 — LUAD

Explore this scatter interactively →