EXOSC7

Across TCGA patient cohorts, EXOSC7 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,434 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EXOSC7-associated proteins across cancer lineages are MTA1, TOP2B, and DHX30. Each is linked with EXOSC7 in more than 5 cancer types. Because this analysis shows association rather than direction, both EXOSC7-to-partner and partner-to-EXOSC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EXOSC7 versus MTA1 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC7→partner) and Y-score (partner→EXOSC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTA1 →	+0.429	+0.321	<.001	<.001	3	6
BRCA	TOP2B →	+0.321	+0.407	<.001	<.001	3	6
BRCA	DHX30 →	+0.221	+0.323	.002	<.001	3	6
OV	MTA1_S522 →	+1.162	+0.435	.002	<.001	3	5
LSCC	MTA1_S576 →	+0.873	+0.451	<.001	<.001	3	5
GBM	NONO →	+0.176	+0.202	.002	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,434 associations by consensus.

EXOSC7 vs MTA1 — GBM

Explore this scatter interactively →