EXOSC7

Across TCGA cell cohorts, EXOSC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,897 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EXOSC7-associated GO terms across cancer lineages are U1 snRNA 3'-end processing, U5 snRNA 3'-end processing, and Cardiolipin biosynthetic process. Each is linked with EXOSC7 in more than 13 cancer types. Because this analysis shows association rather than direction, both EXOSC7-to-partner and partner-to-EXOSC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, U1 snRNA 3'-end processing grouped by EXOSC7-low versus EXOSC7-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC7→partner) and Y-score (partner→EXOSC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	U1 snRNA 3'-end processing →	+0.146	+1.112	.001	<.001	3	14
KIDNEY	U5 snRNA 3'-end processing →	+0.146	+1.112	.001	<.001	3	14
BONE	Cardiolipin biosynthetic process →	+0.142	+1.028	.001	.002	3	12
LUNG_SCLC	Maturation of 5.8S rRNA →	+0.099	+0.733	.001	.002	2	13
BONE	rRNA processing →	+0.096	+0.628	<.001	.003	3	12
BONE	Protein-DNA complex disassembly →	+0.178	+0.853	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,897 associations by consensus.

U1 snRNA 3'-end processing by EXOSC7 expression — KIDNEY

Explore this box plot interactively →