Across TCGA patient cohorts, EXOSC6 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,475 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EXOSC6-associated proteins across cancer lineages are DHX38, EDC4, and HSDL1. Each is linked with EXOSC6 in more than 6 cancer types. Because this analysis shows association rather than direction, both EXOSC6-to-partner and partner-to-EXOSC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC6→partner) and Y-score (partner→EXOSC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DHX38 →	+0.258	+0.446	<.001	<.001	3	7
BRCA	EDC4 →	+0.272	+0.435	<.001	<.001	3	7
UCEC	HSDL1 →	+0.678	+0.447	<.001	.001	3	5
OV	FTO →	+0.356	+0.527	<.001	.005	3	5
LSCC	NUP93 →	+0.186	+0.462	<.001	<.001	3	4
UCEC	ADAT1_S191 →	+0.407	+0.443	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,475 associations by consensus.

Exploration

EXOSC6 survival (RNA) · tumor vs normal (RNA) · all EXOSC6 data types