Across TCGA cell cohorts, EXOSC6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,545 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EXOSC6-associated GO terms across cancer lineages are snRNA processing, snRNA 3'-end processing, and snRNA metabolic process. Each is linked with EXOSC6 in more than 16 cancer types. Because this analysis shows association rather than direction, both EXOSC6-to-partner and partner-to-EXOSC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC6→partner) and Y-score (partner→EXOSC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	snRNA processing →	+0.119	+1.050	.005	.002	3	17
LUNG_NSCLC_LUSC	snRNA 3'-end processing →	+0.110	+0.977	.003	<.001	3	16
OESOPHAGUS	snRNA metabolic process →	+0.067	+0.632	<.001	.008	3	15
URINARY_TRACT	RNA surveillance →	+0.089	+0.822	<.001	<.001	3	15
OVARY	Nuclear RNA surveillance →	+0.085	+1.028	<.001	<.001	3	15
LIVER	Peptidyl-methionine modification →	+0.238	+0.551	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,545 associations by consensus.

Exploration

EXOSC6 survival (RNA) · tumor vs normal (RNA) · all EXOSC6 data types