EXOSC5

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EXOSC5 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EXOSC5-associated genes across cancer lineages are Platelets. Each is linked with EXOSC5 in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOSC5-to-partner and partner-to-EXOSC5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Platelets grouped by EXOSC5-low versus EXOSC5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOSC5→partner) and Y-score (partner→EXOSC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPlatelets →+0.035+2.733.002.04532
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Platelets by EXOSC5 expression — UCEC

Box plot of Platelets in EXOSC5-low vs EXOSC5-high samples in UCEC.

Explore this box plot interactively →

Exploration