EXOSC10-AS1

Across TCGA pan-cancer cohorts, EXOSC10-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated EXOSC10-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher EXOSC10-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EXOSC10-AS1 expression acts as an unfavorable survival marker, although some lineages such as CHOL and COAD show a favorable association.

ACC, KIRC, and LGG are the cancer types where EXOSC10-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.249	0.673	<.001	97	view →
KIRC	OS	Tertile	All	0.567	0.710	.002	72	view →
LGG	DFS	Median	All	0.332	0.469	<.001	50	view →
MESO	OS	Quartile	All	0.301	0.624	<.001	48	view →
LIHC	OS	Quartile	All	0.711	0.884	<.001	32	view →
LUAD	DFS	Quartile	III,IV	0.273	0.624	.024	23	view →
LAML	DFS	Quartile	All	0.367	0.709	<.001	18	view →
SARC	DFS	Quartile	All	0.400	0.705	.003	16	view →
THYM	DFS	Quartile	III,IV	0.312	0.875	.005	12	view →
GBM	DFS	Median	All	0.193	0.318	.004	9	view →
LUSC	OS	Quartile	II,III,IV	0.709	0.835	.030	8	view →
UVM	DFS	Tertile	III,IV	0.368	0.749	.014	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

EXOSC10-AS1–ACC (DFS)

Open the ACC breakdown →