EXOSC10-AS1

Across TCGA pan-cancer cohorts, EXOSC10-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of EXOSC10-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where EXOSC10-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EXOSC10-AS1 is over-expressed in tumor.

BLCA, KIRC, and LUSC are the cancer types where EXOSC10-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EXOSC10-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	All	+1.162	<.001	11	view →
KIRC	All	All	+0.266	<.001	10	view →
LUSC	Female	All	+0.941	<.001	8	view →
LUAD	All	III,IV	+0.771	<.001	8	view →
LIHC	Female	III,IV	+0.718	<.001	8	view →
COAD	Male	II,III,IV	+0.537	<.001	8	view →
THCA	Female	All	+0.405	<.001	7	view →
UCEC	All	III,IV	+1.611	<.001	6	view →
STAD	Male	All	+0.575	<.001	6	view →
HNSC	Male	All	+0.451	<.001	6	view →
PRAD	All	All	+0.522	<.001	2	view →
READ	All	All	+0.517	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

EXOSC10-AS1–BLCA

Open the BLCA breakdown →