EXOC7

Across TCGA patient cohorts, EXOC7 mutation is significantly associated with the RNA expression of many other genes, with 1,962 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EXOC7-associated genes across cancer lineages are CENPH, PGAM1, and BIRC5. Each is linked with EXOC7 in more than 3 cancer types. Because this analysis shows association rather than direction, both EXOC7-to-partner and partner-to-EXOC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPH grouped by EXOC7-low versus EXOC7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC7→partner) and Y-score (partner→EXOC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPH →	+0.633	+2.329	<.001	<.001	3	4
UCEC	PGAM1 →	+0.541	+2.269	.003	<.001	3	4
UCEC	BIRC5 →	+0.519	+2.032	.007	.001	3	4
HNSC	LINC01072 →	+0.141	+4.826	<.001	.001	3	4
UCEC	ZWINT →	+0.622	+1.906	<.001	<.001	3	4
UCEC	TMEM107 →	+0.417	+1.496	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,962 associations by consensus.

CENPH by EXOC7 expression — UCEC

Explore this box plot interactively →