EXOC7

Across TCGA pan-cancer cohorts, EXOC7 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated EXOC7 data layer compared with 10 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher EXOC7 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated EXOC7 expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRC show a favorable association.

BRCA, KIRC, and LUAD are the cancer types where EXOC7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	III,IV	0.585	0.389	<.001	61	view →
KIRC	DFS	Median	All	0.711	0.546	<.001	56	view →
LUAD	OS	Median	III,IV	0.643	0.384	.001	48	view →
ACC	DFS	Tertile	All	0.371	0.770	<.001	42	view →
KICH	OS	Quartile	All	0.560	1.000	.004	29	view →
LIHC	DFS	Quartile	All	0.430	0.593	.003	25	view →
LUSC	DFS	Tertile	III,IV	0.472	1.000	.007	22	view →
LGG	OS	Tertile	All	0.327	0.683	.001	18	view →
HNSC	OS	Quartile	III,IV	0.511	0.881	.001	16	view →
UCEC	OS	Quartile	IV	1.000	0.588	.006	14	view →
MESO	DFS	Tertile	All	0.303	0.669	.012	12	view →
READ	OS	Median	All	0.799	0.475	.031	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

EXOC7–BRCA (DFS)

Open the BRCA breakdown →