EXOC7

Across TCGA patient cohorts, EXOC7 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EXOC7-associated genes across cancer lineages are JNK2, eEF2, and ERK2. Each is linked with EXOC7 in more than 3 cancer types. Because this analysis shows association rather than direction, both EXOC7-to-partner and partner-to-EXOC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by EXOC7-low versus EXOC7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC7→partner) and Y-score (partner→EXOC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.250	+1.938	<.001	.001	3	4
UCEC	eEF2 →	+0.256	+1.392	.029	.019	3	3
UCEC	ERK2 →	+0.222	+1.999	<.001	.002	3	3
UCEC	MEK1 →	+0.360	+1.938	.002	.001	3	3
UCEC	PCNA →	+0.235	+2.807	<.001	.002	3	3
UCEC	GAPDH →	+0.462	+2.169	.009	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

JNK2 by EXOC7 expression — UCEC

Explore this box plot interactively →