EXOC6B

Across TCGA cell cohorts, EXOC6B mutation is significantly associated with the RNA expression of many other genes, with 106 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EXOC6B-associated genes across cancer lineages are VCX2, OR8B8, and ARSF. Each is linked with EXOC6B in more than 1 cancer types. Because this analysis shows association rather than direction, both EXOC6B-to-partner and partner-to-EXOC6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VCX2 grouped by EXOC6B-low versus EXOC6B-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXOC6B→partner) and Y-score (partner→EXOC6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	VCX2 →	+0.125	+4.017	<.001	.007	3	1
OESOPHAGUS	OR8B8 →	+0.024	+4.392	<.001	.003	3	1
OESOPHAGUS	ARSF →	+0.032	+4.392	<.001	.003	3	1
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1
BREAST	PABPC1L2A →	+0.083	+5.169	<.001	.005	3	1
BREAST	OR10T2 →	+0.183	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 106 associations by consensus.

VCX2 by EXOC6B expression — OESOPHAGUS

Explore this box plot interactively →