Across TCGA cell cohorts, EXD3 mutation is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EXD3-associated genes across cancer lineages are OR8B4, ADIPOQ, and ZNF683. Each is linked with EXD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both EXD3-to-partner and partner-to-EXD3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EXD3→partner) and Y-score (partner→EXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR8B4 →	+0.015	+4.807	<.001	.003	3	3
SKIN	ADIPOQ →	+0.004	+3.632	<.001	.003	3	2
CNS	ZNF683 →	+0.029	+4.321	.003	.002	3	1
CNS	PRB3 →	+0.109	+3.774	<.001	.008	3	1
CNS	KRTAP1-4 →	+0.056	+4.169	<.001	.008	3	1
CNS	VN1R4 →	+0.058	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

Exploration

EXD3 survival (RNA) · tumor vs normal (RNA) · all EXD3 data types