EWSR1

Across TCGA patient cohorts, EWSR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EWSR1-associated proteins across cancer lineages are MCM3, SMU1, and CTDSPL2. Each is linked with EWSR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both EWSR1-to-partner and partner-to-EWSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EWSR1 versus MCM3 in GBM, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EWSR1→partner) and Y-score (partner→EWSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCM3 →	+0.609	+0.295	.006	.002	3	6
GBM	SMU1 →	+0.199	+0.336	.005	<.001	3	5
GBM	CTDSPL2 →	+0.344	+0.228	<.001	<.001	3	5
GBM	MCM5 →	+0.588	+0.271	.006	.005	3	5
COAD	MCM6 →	+0.493	+0.445	.001	.002	3	5
GBM	MCM7 →	+0.520	+0.220	.001	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,886 associations by consensus.

EWSR1 vs MCM3 — GBM

Explore this scatter interactively →