Across TCGA patient cohorts, EVPLL protein abundance is significantly associated with the RNA expression of many other genes, with 403 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EVPLL-associated genes across cancer lineages are BTN3A3, RAB29, and ELOVL3. Each is linked with EVPLL in more than 1 cancer types. Because this analysis shows association rather than direction, both EVPLL-to-partner and partner-to-EVPLL results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVPLL→partner) and Y-score (partner→EVPLL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	BTN3A3 →	+0.560	+0.449	.006	<.001	3	1
LUAD	RAB29 →	+0.481	+0.372	.002	.005	3	1
LUAD	ELOVL3 →	+0.546	+0.400	.001	.002	3	1
LUAD	GOT1 →	-0.858	-0.360	<.001	.007	3	1
LUAD	LINC00544 →	+0.237	+0.374	.008	.005	3	1
LUAD	PGPEP1 →	+0.382	+0.358	.005	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 403 associations by consensus.

Exploration

EVPLL survival (RNA) · tumor vs normal (RNA) · all EVPLL data types