EVPL

Across TCGA cell cohorts, EVPL RNA expression is significantly associated with the go_rna of many other GO terms, with 3,552 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible EVPL-associated GO terms across cancer lineages are Regulation of clathrin coat assembly, Response to indole-3-methanol, and Bundle of His cell to Purkinje myocyte communication. Each is linked with EVPL in more than 11 cancer types. Because this analysis shows association rather than direction, both EVPL-to-partner and partner-to-EVPL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of clathrin coat assembly grouped by EVPL-low versus EVPL-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EVPL→partner) and Y-score (partner→EVPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of clathrin coat assembly →	+0.223	+2.340	<.001	<.001	3	12
URINARY_TRACT	Response to indole-3-methanol →	+0.258	+3.623	<.001	<.001	3	11
BREAST	Bundle of His cell to Purkinje myocyte communication →	+0.366	+1.757	.003	<.001	3	11
STOMACH	Desmosome assembly →	+0.395	+2.840	<.001	<.001	3	11
URINARY_TRACT	Mammary gland development →	+0.126	+3.241	<.001	<.001	3	11
OESOPHAGUS	Rho protein signal transduction →	+0.196	+2.426	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,552 associations by consensus.

Regulation of clathrin coat assembly by EVPL expression — URINARY_TRACT

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