EVI5L

Across TCGA cell cohorts, EVI5L mutation is significantly associated with the RNA expression of many other genes, with 1,121 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EVI5L-associated genes across cancer lineages are FAM9A, LCE2A, and TMEM114. Each is linked with EVI5L in more than 1 cancer types. Because this analysis shows association rather than direction, both EVI5L-to-partner and partner-to-EVI5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM9A grouped by EVI5L-low versus EVI5L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVI5L→partner) and Y-score (partner→EVI5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM9A →	+0.014	+4.539	<.001	.007	3	1
BLOOD_Leukemia	LCE2A →	+0.053	+4.969	<.001	.003	3	1
BLOOD_Leukemia	TMEM114 →	+0.038	+4.539	<.001	.007	3	1
BLOOD_Leukemia	SPO11 →	+0.019	+4.969	<.001	.003	3	1
LARGE_INTESTINE	GRK3 →	+0.790	+2.588	.001	.004	3	1
LARGE_INTESTINE	ANKRD54 →	+0.493	+2.588	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,121 associations by consensus.

FAM9A by EVI5L expression — BLOOD_Leukemia

Explore this box plot interactively →