EVI5L

Across TCGA cell cohorts, EVI5L mutation is significantly associated with the mutation status of many other genes, with 5,445 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EVI5L-associated genes across cancer lineages are PCDHA4, SOX7, and PCDHA2. Each is linked with EVI5L in more than 3 cancer types. Because this analysis shows association rather than direction, both EVI5L-to-partner and partner-to-EVI5L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCDHA4 grouped by EVI5L-low versus EVI5L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVI5L→partner) and Y-score (partner→EVI5L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PCDHA4 →	+2.779	+4.326	.006	.006	1	4
LARGE_INTESTINE	SOX7 →	+2.767	+2.409	.001	.001	1	4
STOMACH	PCDHA2 →	+4.807	+4.807	.008	.008	1	4
LARGE_INTESTINE	PCDH8 →	+2.641	+3.939	<.001	<.001	1	4
STOMACH	ABCF3 →	+4.807	+4.807	.008	.008	1	4
LARGE_INTESTINE	SCARF1 →	+2.504	+2.129	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,445 associations by consensus.

PCDHA4 by EVI5L expression — BLOOD_Leukemia

Explore this box plot interactively →