Across TCGA patient cohorts, EVI2B mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EVI2B-associated genes across cancer lineages are EGFR_pY1068, Shc_pY317, and Tuberin. Each is linked with EVI2B in more than 1 cancer types. Because this analysis shows association rather than direction, both EVI2B-to-partner and partner-to-EVI2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EVI2B→partner) and Y-score (partner→EVI2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.317	-3.000	.028	.037	3	1
UCEC	Shc_pY317 →	-0.276	-3.000	.001	.036	3	1
UCEC	Tuberin →	+0.403	+3.000	.009	.037	3	1
UCEC	BRCA2 →	-0.160	-2.992	.029	.036	3	1
UCEC	GATA6 →	-0.210	-2.992	.018	.036	2	1
UCEC	p38-MAPK →	-0.198	-3.000	.037	.037	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

EVI2B survival (RNA) · tumor vs normal (RNA) · all EVI2B data types