EVI2A

Across TCGA cell cohorts, EVI2A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,157 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EVI2A-associated GO terms across cancer lineages are Positive regulation of focal adhesion assembly, Regulation of plasminogen activation, and Positive regulation of cell-substrate junction organization. Each is linked with EVI2A in more than 11 cancer types. Because this analysis shows association rather than direction, both EVI2A-to-partner and partner-to-EVI2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of focal adhesion assembly grouped by EVI2A-low versus EVI2A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EVI2A→partner) and Y-score (partner→EVI2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of focal adhesion assembly →	+0.213	+1.980	<.001	<.001	3	12
BONE	Regulation of plasminogen activation →	+0.314	+3.170	<.001	<.001	3	12
BONE	Positive regulation of cell-substrate junction organization →	+0.168	+1.946	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of establishment of T cell polarity →	+0.274	+1.976	<.001	<.001	3	12
BONE	Negative regulation of Rho protein signal transduction →	+0.178	+1.941	<.001	<.001	3	12
SOFT_TISSUE	Positive regulation of fibroblast proliferation →	+0.115	+1.756	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,157 associations by consensus.

Positive regulation of focal adhesion assembly by EVI2A expression — BONE

Explore this box plot interactively →