EVC2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EVC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,743 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible EVC2-associated proteins across cancer lineages are FERMT2, DENND2B, and FLNA. Each is linked with EVC2 in more than 7 cancer types. Because this analysis shows association rather than direction, both EVC2-to-partner and partner-to-EVC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EVC2 versus FERMT2 in UCEC, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EVC2→partner) and Y-score (partner→EVC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFERMT2 →+0.583+0.720.003.00238
BRCADENND2B →+0.465+0.686<.001<.00137
UCECFLNA →+0.662+0.752.001.00237
COADHSPG2 →+0.567+0.393<.001<.00137
BRCAPPFIBP1 →+0.349+0.521<.001<.00137
LSCCMRPS22 →-0.360-0.604<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,743 associations by consensus.

EVC2 vs FERMT2 — UCEC

Per-sample scatter of EVC2 vs FERMT2 in UCEC (Pearson r = 0.30).

Explore this scatter interactively →

Exploration