ETV7

Across TCGA cell cohorts, ETV7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,965 significant associations in total. CNS shows the largest number of these associations.

The most reproducible ETV7-associated GO terms across cancer lineages are Xenophagy, Pattern recognition receptor signaling pathway, and Antigen processing and presentation of peptide antigen via MHC class I. Each is linked with ETV7 in more than 14 cancer types. Because this analysis shows association rather than direction, both ETV7-to-partner and partner-to-ETV7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Xenophagy grouped by ETV7-low versus ETV7-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV7→partner) and Y-score (partner→ETV7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Xenophagy →	+0.158	+0.852	<.001	.002	3	15
UPPER_AERODIGESTIVE_TRACT	Pattern recognition receptor signaling pathway →	+0.081	+1.458	<.001	<.001	3	15
BREAST	Antigen processing and presentation of peptide antigen via MHC class I →	+0.228	+1.547	<.001	<.001	3	15
BLOOD_Lymphoma	Cytoplasmic pattern recognition receptor signaling pathway →	+0.072	+1.587	<.001	<.001	3	15
PANCREAS	Intrinsic apoptotic signaling pathway →	+0.062	+1.407	<.001	<.001	3	14
BREAST	Antigen processing and presentation of endogenous antigen →	+0.311	+1.525	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,965 associations by consensus.

Xenophagy by ETV7 expression — CNS

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