ETV7

Across TCGA pan-cancer cohorts, ETV7 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ETV7 data layer compared with 2 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ETV7 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ETV7 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BLCA show a favorable association.

SKCM, BLCA, and UVM are the cancer types where ETV7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	All	0.420	0.273	<.001	128	view →
BLCA	OS	Median	All	0.530	0.334	<.001	117	view →
UVM	OS	Tertile	All	0.443	0.835	<.001	84	view →
ACC	OS	Median	All	0.439	0.783	.001	81	view →
CESC	OS	Tertile	All	0.936	0.773	<.001	70	view →
HNSC	DFS	Median	II,III,IV	0.397	0.248	.001	56	view →
LGG	OS	Median	All	0.719	0.893	<.001	51	view →
MESO	OS	Quartile	All	0.492	0.252	.003	39	view →
PAAD	DFS	Median	All	0.392	0.567	<.001	32	view →
LAML	DFS	Tertile	All	0.245	0.645	<.001	30	view →
READ	DFS	Median	All	0.915	0.695	.008	28	view →
OV	OS	Median	All	0.375	0.273	.002	26	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ETV7–SKCM (OS)

Open the SKCM breakdown →