ETV7

Across TCGA cell cohorts, ETV7 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ETV7-associated genes across cancer lineages are ASB17, KLHL40, and C12orf40. Each is linked with ETV7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ETV7-to-partner and partner-to-ETV7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by ETV7-low versus ETV7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV7→partner) and Y-score (partner→ETV7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.014	+4.222	<.001	.006	3	1
OVARY	KLHL40 →	+0.007	+4.865	.001	<.001	3	1
OVARY	C12orf40 →	+0.010	+4.444	<.001	.001	3	1
OVARY	C1orf146 →	+0.040	+4.865	<.001	<.001	3	1
LARGE_INTESTINE	SEPTIN14 →	+0.009	+3.684	<.001	.006	3	1
LARGE_INTESTINE	ITGAD →	+0.018	+4.510	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ASB17 by ETV7 expression — OVARY

Explore this box plot interactively →