ETV5-AS1

Across TCGA pan-cancer cohorts, ETV5-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ETV5-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ETV5-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ETV5-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

ACC, UVM, and LGG are the cancer types where ETV5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	II,III,IV	0.289	0.696	.001	61	view →
UVM	DFS	Tertile	III,IV	0.229	0.815	<.001	61	view →
LGG	OS	Median	All	0.846	0.941	<.001	34	view →
THCA	DFS	Tertile	II,III,IV	0.863	0.946	.008	31	view →
UCS	OS	Median	II,III,IV	0.564	0.265	.022	28	view →
BLCA	OS	Quartile	III,IV	0.434	0.580	.007	28	view →
READ	DFS	Quartile	III,IV	0.548	0.867	.006	28	view →
OV	OS	Median	All	0.264	0.370	.006	28	view →
UCEC	DFS	Quartile	All	0.783	0.859	.014	28	view →
KICH	OS	Quartile	All	0.499	0.942	.016	16	view →
LIHC	OS	Quartile	All	0.588	0.752	.010	14	view →
KIRC	DFS	Median	II,III,IV	0.425	0.625	.021	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ETV5-AS1–ACC (DFS)

Open the ACC breakdown →