ETV3L

Across TCGA pan-cancer cohorts, ETV3L RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ETV3L data layer compared with 6 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ETV3L RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ETV3L expression acts as an unfavorable survival marker, although some lineages such as HNSC and ESCA show a favorable association.

KIRC, LIHC, and HNSC are the cancer types where ETV3L RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	IV	0.338	0.773	<.001	72	view →
LIHC	OS	Tertile	All	0.398	0.579	.001	56	view →
HNSC	DFS	Tertile	II,III,IV	0.386	0.262	.003	50	view →
ESCA	DFS	Median	IV	0.634	0.205	.006	42	view →
SCLC	OS	Quartile	All	0.509	0.174	.003	36	view →
LUAD	DFS	Median	All	0.737	0.574	.003	30	view →
GBM	DFS	Quartile	All	0.175	0.422	.001	18	view →
KIRP	OS	Median	All	0.934	0.835	.009	18	view →
OV	OS	Quartile	III,IV	0.825	0.880	.022	18	view →
READ	DFS	Tertile	III,IV	0.308	0.699	.013	16	view →
BRCA	DFS	Quartile	All	0.683	0.454	.010	12	view →
LUSC	DFS	Tertile	II,III,IV	0.510	0.818	.010	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ETV3L–KIRC (DFS)

Open the KIRC breakdown →