ETV3

Across TCGA cell cohorts, ETV3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,803 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ETV3-associated GO terms across cancer lineages are Positive regulation of TORC2 signaling, Regulation of mRNA catabolic process, and Positive regulation of mRNA metabolic process. Each is linked with ETV3 in more than 15 cancer types. Because this analysis shows association rather than direction, both ETV3-to-partner and partner-to-ETV3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of TORC2 signaling grouped by ETV3-low versus ETV3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV3→partner) and Y-score (partner→ETV3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of TORC2 signaling →	+0.115	+1.117	.006	.001	3	16
LUNG_NSCLC_LUSC	Regulation of mRNA catabolic process →	+0.056	+1.040	<.001	.003	3	15
STOMACH	Positive regulation of mRNA metabolic process →	+0.074	+0.730	<.001	.001	3	14
LUNG_NSCLC_LUSC	Heterochromatin formation →	+0.080	+1.208	.001	.008	3	14
STOMACH	Regulation of protein sumoylation →	+0.120	+1.008	.002	<.001	3	14
STOMACH	Epigenetic regulation of gene expression →	+0.072	+0.961	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,803 associations by consensus.

Positive regulation of TORC2 signaling by ETV3 expression — BLOOD_Myeloma

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