ETV2

Across TCGA pan-cancer cohorts, ETV2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ETV2 data layer compared with 23 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ETV2 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ETV2 expression acts as an unfavorable survival marker.

BLCA, LUAD, and LUSC are the cancer types where ETV2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.153	0.720	<.001	45	view →
LUAD	OS	Median	All	0.141	0.812	<.001	24	view →
LUSC	OS	Median	II,III,IV	0.002	0.743	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ETV2–BLCA (OS)

Open the BLCA breakdown →