ETV2

Across TCGA cell cohorts, ETV2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUSC shows the largest number of these associations.

The most reproducible ETV2-associated genes across cancer lineages are MDFIC2. Each is linked with ETV2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ETV2-to-partner and partner-to-ETV2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MDFIC2 grouped by ETV2-low versus ETV2-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETV2→partner) and Y-score (partner→ETV2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MDFIC2 →	+0.026	+4.643	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

MDFIC2 by ETV2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →