ETS1

Across TCGA cell cohorts, ETS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,878 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ETS1-associated GO terms across cancer lineages are PML body organization, Nuclear body organization, and Protein import into peroxisome membrane. Each is linked with ETS1 in more than 17 cancer types. Because this analysis shows association rather than direction, both ETS1-to-partner and partner-to-ETS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by ETS1-low versus ETS1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ETS1→partner) and Y-score (partner→ETS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	PML body organization →	+0.235	+3.831	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Nuclear body organization →	+0.130	+3.363	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Protein import into peroxisome membrane →	+0.137	+4.022	.001	<.001	3	14
BONE	Dentinogenesis →	+2.166	+3.764	<.001	<.001	3	14
BONE	Regulation of protein K48-linked ubiquitination →	+0.149	+2.728	.001	.006	3	14
BONE	Regulation of hemostasis →	+0.184	+3.511	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,878 associations by consensus.

PML body organization by ETS1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →