ETNK1

Across TCGA patient cohorts, ETNK1 mutation is significantly associated with the RNA expression of many other genes, with 2,269 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ETNK1-associated genes across cancer lineages are OR5M6P, REXO1L8P, and MIR7976. Each is linked with ETNK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ETNK1-to-partner and partner-to-ETNK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5M6P grouped by ETNK1-low versus ETNK1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETNK1→partner) and Y-score (partner→ETNK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR5M6P →	+0.272	+5.378	.008	.006	3	2
BRCA	REXO1L8P →	+0.062	+6.950	<.001	<.001	3	2
UCEC	MIR7976 →	+0.241	+1.737	.005	.008	3	2
UCEC	HNRNPCL3 →	+0.032	+1.734	<.001	.005	3	2
BRCA	NUP210P1 →	+0.088	+5.122	<.001	.008	3	2
BLCA	SNORD116-3 →	+0.261	+3.266	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,269 associations by consensus.

OR5M6P by ETNK1 expression — BRCA

Explore this box plot interactively →