ETNK1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ETNK1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ETNK1-associated genes across cancer lineages are MMP26 and C10orf53. Each is linked with ETNK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ETNK1-to-partner and partner-to-ETNK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by ETNK1-low versus ETNK1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ETNK1→partner) and Y-score (partner→ETNK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMMP26 →+0.033+3.217<.001.00631
LARGE_INTESTINEC10orf53 →+0.010+3.217.002.00631
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MMP26 by ETNK1 expression — LARGE_INTESTINE

Box plot of MMP26 in ETNK1-low vs ETNK1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration