Across TCGA cell cohorts, ESRRG mutation is significantly associated with the mutation status of many other genes, with 1,702 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ESRRG-associated genes across cancer lineages are TRHDE, ZFPM2, and DCAF12L1. Each is linked with ESRRG in more than 3 cancer types. Because this analysis shows association rather than direction, both ESRRG-to-partner and partner-to-ESRRG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESRRG→partner) and Y-score (partner→ESRRG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TRHDE →	+3.832	+4.316	.002	.002	1	4
LARGE_INTESTINE	ZFPM2 →	+2.043	+3.693	.009	.009	1	4
LUNG_NSCLC_LUAD	DCAF12L1 →	+3.117	+4.491	.004	.004	1	3
LUNG_NSCLC_LUAD	OR5D16 →	+3.339	+4.662	.003	.003	1	3
LUNG_NSCLC_LUAD	TMEM67 →	+5.339	+4.772	.004	.004	1	3
LUNG_NSCLC_LUAD	PCDHA6 →	+3.339	+4.662	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,702 associations by consensus.

Exploration

ESRRG survival (RNA) · tumor vs normal (RNA) · all ESRRG data types