Across TCGA patient cohorts, ESPN protein abundance is significantly associated with the protein abundance of many other proteins, with 9,851 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ESPN-associated proteins across cancer lineages are ESPN_S342, ESPN_T649, and DOCK11. Each is linked with ESPN in more than 6 cancer types. Because this analysis shows association rather than direction, both ESPN-to-partner and partner-to-ESPN results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ESPN→partner) and Y-score (partner→ESPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ESPN_S342 →	+1.544	+0.820	<.001	<.001	3	7
LSCC	ESPN_T649 →	+1.412	+0.611	<.001	<.001	3	5
UCEC	DOCK11 →	-0.437	-0.628	<.001	<.001	3	4
LSCC	DLGAP4_T915 →	+0.643	+0.691	<.001	<.001	3	4
OV	CAPS →	+1.544	+0.591	<.001	.005	3	4
UCEC	NUDC →	+0.376	+0.863	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,851 associations by consensus.

Exploration

ESPN survival (RNA) · tumor vs normal (RNA) · all ESPN data types