Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, ESPN mutation is significantly associated with the RNA expression of many other genes, with 1,539 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible ESPN-associated genes across cancer lineages are TBRG1, BUB3, and FANCC. Each is linked with ESPN in more than 1 cancer types. Because this analysis shows association rather than direction, both ESPN-to-partner and partner-to-ESPN results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (ESPN→partner) and Y-score (partner→ESPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.