ESM1

Across TCGA patient cohorts, ESM1 RNA expression is significantly associated with the RNA expression of many other genes, with 17,681 significant associations in total. THYM shows the largest number of these associations.

The most reproducible ESM1-associated genes across cancer lineages are FLT1, APLN, and DLL4. Each is linked with ESM1 in more than 33 cancer types. Because this analysis shows association rather than direction, both ESM1-to-partner and partner-to-ESM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESM1 versus FLT1 in KIRC, with a Pearson correlation of 0.86.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESM1→partner) and Y-score (partner→ESM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIRC	FLT1 →	+1.710	+1.707	<.001	<.001	3	34
TGCT	APLN →	+3.099	+2.895	<.001	<.001	3	32
UVM	DLL4 →	+1.589	+0.929	<.001	<.001	3	32
TGCT	ANGPT2 →	+2.009	+2.786	<.001	<.001	3	32
TGCT	STC1 →	+2.782	+2.878	<.001	<.001	3	32
THYM	VEGFA →	+1.667	+1.535	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,681 associations by consensus.

ESM1 vs FLT1 — KIRC

Explore this scatter interactively →