ESCO2

Across TCGA patient cohorts, ESCO2 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,068 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ESCO2-associated proteins across cancer lineages are RRM1, RRM2, and RRM2_S20. Each is linked with ESCO2 in more than 9 cancer types. Because this analysis shows association rather than direction, both ESCO2-to-partner and partner-to-ESCO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESCO2 versus RRM1 in UCEC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ESCO2→partner) and Y-score (partner→ESCO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM1 →	+0.456	+0.825	<.001	<.001	3	10
LUAD	RRM2 →	+0.945	+0.935	<.001	<.001	3	10
LUAD	RRM2_S20 →	+1.547	+0.856	<.001	<.001	3	10
GBM	SMC2 →	+0.777	+1.119	<.001	<.001	3	10
GBM	SMC4 →	+0.742	+1.079	<.001	<.001	3	10
LUAD	CDC20_T70 →	+1.204	+0.900	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,068 associations by consensus.

ESCO2 vs RRM1 — UCEC

Explore this scatter interactively →