ERVMER61-1

Across TCGA patient cohorts, ERVMER61-1 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ERVMER61-1-associated genes across cancer lineages are RNA5SP170, RPSAP67, and CATSPERE. Each is linked with ERVMER61-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ERVMER61-1-to-partner and partner-to-ERVMER61-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP170 grouped by ERVMER61-1-low versus ERVMER61-1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ERVMER61-1→partner) and Y-score (partner→ERVMER61-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP170 →	+0.376	+5.382	<.001	.003	3	1
BRCA	RPSAP67 →	+0.344	+4.766	<.001	.003	3	1
UCEC	CATSPERE →	-0.360	-3.448	.005	.005	3	1
UCEC	SNORD114-7 →	+0.276	+4.292	.001	<.001	3	1
UCEC	RNU6-48P →	+0.579	+2.762	.001	.002	3	1
UCEC	RNU6-166P →	+0.118	+4.148	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

RNA5SP170 by ERVMER61-1 expression — BRCA

Explore this box plot interactively →